Por favor utiliza este link para citar o compartir este documento: http://repositoriodigital.academica.mx/jspui/handle/987654321/103613
Título: Farmacovigilancia de medicamentos no inhalados en pacientes hospitalizados con enfermedades broncopulmonares
Pharmacovigilance of drugs not inhaled in hospitalized patients with broncopulmonar disease
Autores: 
Palabras clave: Reacciones adversas; farmacovigilancia; enfermedades broncopulmonares; medicamentos
Adverse reaction; pharmacovigilance; drugs; broncopulmonars disease
Fecha de publicación: 3-Oct-2012
Editorial: Facultad de Estudios Superiores Zaragoza
Descripción: Es conocido que todos los medicamentos pueden causar reacciones adversas que pueden variar desde moderadas hasta graves que ponen en peligro la vida del paciente. Para detectar la presencia de reacciones adversas de los medicamentos no inhalados, en pacientes hospitalizados en una clínica de Enfermedad Pulmonar Obstructiva Crónica (EPOC) así como la severidad y causalidad, se llevo a cabo un estudio prospectivo y transversal, de enero a octubre de 2006. Se monitoreo a los pacientes desde su ingreso hasta su egreso, interrogando a los pacientes, revisando su expediente clínico y la hoja de enfermería, elaborando un registro diario de diagnóstico, tratamiento y reacciones adversas potenciales. Se uso la definición de reacción adversa propuesta por la OMS y se aplicó estadística descriptiva. De los 204 pacientes hospitalizados en este periodo sólo 60 (29.4%) presentaron reacciones adversas. 65% hombres y 35% mujeres, con edad promedio de 59.53 años, una estancia hospitalaria promedio de 19 días y un número promedio de medicamentos prescritos de 9. Los diagnósticos principales fueron: EPOC (VEF1 40.12% y VEF1/CVF 61.93%) 46.7%, asma 15%, neumonía 8.3% y otras. Los fármacos implicados fueron: metilprednisolona 26.67%, ceftriaxona 8.33%, ciprofloxacina 10% y heparina 11.67%. En cuanto a su severidad: se encontraron el 7.14% leves, el 87.14% moderadas y el 5.71% graves. Se encontró un porcentaje mayor de reacciones adversas que las reportadas a nivel internacional en pacientes hospitalizados.
It is known that all medicines can cause adverse reactions. This reactions rank from moderate to severe adverse reactions which can risk patient life. To detect the presence of adverse reactions of not inhaled drugs in hospitalized patients at a Chronic Obstructive Pulmonary Disease (COPD) clinic as well as severity and causality, a prospective and transversal study was performed from January to October of 2006. The patients were monitored from their admission to their egress, asking the patients, ckecking their clinical history and their nursery inform, making a daily diagnostic, treatment and potential adverse reactions registry. The adverse reaction definition proposed by WHO was used. Descriptive statistic was applied. Overall, 60 (29.4%) adverse drug reaction were detected in 204 hospitalized patients in this period. 65% were men and 35% were women with average age of 59.53 years and a 19 days average stay at hospital, with and average number of prescribed drugs of 9. The 46.7% with COPD (VEF1 40.12% y VEF1/CVF 61.93%), asthma 15%, pneumonia 8.3% and others. The implicated drugs were: methylprednisolone 26.67%, ceftriaxone 8.33%, ciprofloxacin 10% and heparin 11.67%. About the severity it was found that 7.14% were mild, 87.14% were moderately and 5.71% serious. It was found that a higher percentage of adverse reactions were developed in these patients than those reported at international level.
Other Identifiers: http://revistas.unam.mx/index.php/vertientes/article/view/26698
Aparece en las Colecciones:Vertientes. Revista Especializada en Ciencias de la Salud

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